21 Results for "

Catalpa bungei C. A. Mey.

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "Catalpa bungei C. A. Mey." in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N1983
CAS No.: 38395-02-7
Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease .
Cat. No.: HY-N3706
CAS No.: 15297-92-4
Target:  

Fungal

Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC50 value 0.41 mg/L .
Cat. No.: HY-N16598
CAS No.: 887140-17-2
4''-O-Methylcatalposide (compound 7) is a glycoside from the stem bark of Catalpa ovata. 4''-O-Methylcatalposide exhibits peroxynitrite (ONOO )-scavenging activity with an IC50 of 36.4 μM. 4''-O-Methylcatalposide can be used for anti-inflammatory research .
Cat. No.: HY-N1983R
CAS No.: 38395-02-7
Caudatin (Standard) is the analytical standard of Caudatin (HY-N1983). This product is intended for research and analytical applications. Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease .
Cat. No.: HY-149716
CAS No.: 3047891-88-0
Research Areas:  

Cancer

MEY-003 is an Autotaxin(ATX) inhibitor with EC50s of 460 nM and 1.09 μM for hATX-β and hATX-ɣ (analysis with LPC18:1). MEY-003 behaves as a non-competitive inhibitor with K iof 432 nM. MEY-003 can be used for targeted ATX-related disease research .
Cat. No.: HY-N12547
CAS No.: 1011714-20-7
19-OD-Carboxyglucopyranosyl-12-O--D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene was isolated from the acetone-soluble extract of Clerodendrum bungei roots .
Cat. No.: HY-N9731
CAS No.: 202337-44-8
6-O-p-Hydroxybenzoylglutinoside acts as a selective NF-κB inhibitor that suppresses the transcriptional activity of TNF-α-activated NF-κB (IC50=52.78 μM). 6-O-p-Hydroxybenzoylglutinoside shows no significant inhibitory activity against sEH, AChE, or BChE. 6-O-p-Hydroxybenzoylglutinoside is a caged chlorinated iridoid glycoside identified from the seeds of Catalpa bungei (Manchurian catalpa) .
Cat. No.: HY-N11789
CAS No.: 100205-29-6
3-Hydroxyirisquinone is a quinone derivative, which can isolated from the seeds of Iris bungei Maxim .
Cat. No.: HY-N1206
CAS No.: 72514-90-0
Synonyms: 6-O-(E)-p-Coumaroylcatalpol
Specioside is a novel iridoid glycoside extracted from Catalpa speciosa Warder (Bignoniaceae) .
Cat. No.: HY-N6088
CAS No.: 166040-90-0
Isoginsenoside-Rh3 is a triterpenoid saponin from the fruits of Panax ginseng C. A. Mey .
Cat. No.: HY-N9485
CAS No.: 83349-37-5
Target:  

Others

25(R)-Hydroxyprotopanaxadiol is a Triterpenoids product that can be isolated from the roots of Panax ginseng C. A. Mey. .
Cat. No.: HY-N2797
CAS No.: 35241-80-6
9-Methoxy-α-lapachone is a Quinones product that can be isolated from the stems of Catalpa ovata .
Cat. No.: HY-N1886
CAS No.: 56473-67-7
Catalpanp-1 is a potent anti-microbial agent. Catalpanp-1 has strong antimicrobial effect on yeast, bacteria, fungi and the like .
Cat. No.: HY-N2726
CAS No.: 355143-38-3
6'-O-p-Hydroxybenzoylcatalposide is a Iridoids product that can be isolated from the leaves of Catalpa ovata G. Don. .
Cat. No.: HY-N10079
CAS No.: 50816-74-5
Synonyms: Jatrophan
Suchilactone (Jatrophan) is a lignan extracted from Monsonia angustifolia E.Mey. Suchilactone binds to SHP2 and inhibits SHP2 activation, thereby inhibiting ERK-mediated cell proliferation. Suchilactone can be ued in acute myeloid leukaemia (AML) .
Cat. No.: HY-N3552
CAS No.: 6736-85-2
Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages .
Cat. No.: HY-N7909
CAS No.: 71035-02-4
1-Octacosanoyl glyceride is a natural compound that can be found in the wood of Catalpa ovate .
Cat. No.: HY-N1627
CAS No.: 16274-34-3
2-Prenyl-1-naphthol is a Sesquiterpenoids product that can be isolated from the herbs of Catalpa ovata .
Cat. No.: HY-N2722
CAS No.: 136807-41-5
6-O-Cinnamoylcatalpol is a Iridoids product that can be isolated from the herbs of Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey .
Cat. No.: HY-N2731
CAS No.: 124168-04-3
6-O-Vanilloylajugol is a Iridoids product that can be isolated from the herbs of Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey. .